Closure Protocol
A standardized closure-stage sequence that integrates Simini Protect Lavage as an adjunctive lavage step
prior to final saline irrigation and layered closure.
This protocol supports repeatable closure workflows and does not replace clinical judgment.
Where Simini fits in the case
A closure-stage sequence showing where the adjunctive lavage step occurs prior to final saline
irrigation.
The steps below describe a closure-stage workflow. Exact technique and timing remain surgeon-directed.
- Step 1 —Complete definitive orthopedic work.
- Step 2 —Apply Simini Protect Lavage as an adjunctive lavage
step during the closure phase.
- Step 3 —Allow appropriate dwell time in accordance with the
User Guide.
- Step 4 —Perform final saline irrigation.
- Step 5 —Proceed with routine layered closure.
What does not change
- No change to instrumentation or implant strategy
- No change to reduction, fixation, or primary operative sequence
- No change to systemic antibiotic protocols
- Final saline irrigation remains part of standard closure
- Intended to be reproducible across surgeons, staff, and case complexity
Use considerations
- Used as a closure-stage adjunct within orthopedic workflows
- Applied prior to final saline irrigation and layered closure
- Applicable across routine and higher-complexity orthopedic procedures
- Not for use in eyes, ears, abdomen or thorax
- Refer to the User Guide and Instructions for Use for handling guidance and contraindications
Safety & compatibility
- Non-antibiotic; does not replace or interfere with systemic antibiotic protocols
- Evaluated for compatibility with commonly used orthopedic implant materials
- No known adverse effects on wound healing when used as directed
- Intended for orthopedic-associated exposure during closure
- Refer to the User Guide and Instructions for Use for contraindications and handling guidance
Use in practice
Simini Protect Lavage is used within a range of veterinary orthopedic practice settings, including
referral hospitals, specialty surgical centers, and mobile or multi-site surgical workflows.