Rustemeyer et al: Extravasation of Intraarticular Fluid Injection Following Canine Elbow Arthroscopy: A Cadaveric Study
Veterinary and Comparative Orthopaedics and Traumatology 1, 2026

Extravasation of Intraarticular Fluid Injection Following Canine Elbow Arthroscopy: A Cadaveric Study

🔍 Key Findings

  • Elbow arthroscopy significantly increased periarticular extravasation of injected contrast compared with simple arthrocentesis (mean volume 11,663 mm³ vs 6,548 mm³; p < 0.0001).
  • Contrast intensity was significantly lower after arthroscopy (739 HU vs 2,069 HU), indicating dilution and leakage into surrounding tissues.
  • Extravasation occurred immediately after injection, with no significant changes in volume or intensity during the 15-minute observation period.
  • Average difference in contrast volume was ~5,115 mm³ greater after arthroscopy, supporting portal-related fluid leakage.
  • Diffuse periarticular spread of contrast was observed on CT in arthroscopy joints, whereas arthrocentesis controls maintained well-contained intraarticular contrast.
  • Cadaveric CT imaging with 3D segmentation effectively quantified intra- and extracapsular contrast distribution.
  • Dilutional effects (≈64% reduction in intensity) suggest both irrigation fluid residue and tissue diffusion contribute to extravasation.
  • Clinical implication: intraarticular therapeutics (e.g., orthobiologics) may achieve higher effective concentrations if injected later rather than immediately after arthroscopy.

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Rustemeyer et al: Extravasation of Intraarticular Fluid Injection Following Canine Elbow Arthroscopy: A Cadaveric Study
Veterinary and Comparative Orthopaedics and Traumatology 1, 2026

🔍 Key Findings

  • Elbow arthroscopy significantly increased periarticular extravasation of injected contrast compared with simple arthrocentesis (mean volume 11,663 mm³ vs 6,548 mm³; p < 0.0001).
  • Contrast intensity was significantly lower after arthroscopy (739 HU vs 2,069 HU), indicating dilution and leakage into surrounding tissues.
  • Extravasation occurred immediately after injection, with no significant changes in volume or intensity during the 15-minute observation period.
  • Average difference in contrast volume was ~5,115 mm³ greater after arthroscopy, supporting portal-related fluid leakage.
  • Diffuse periarticular spread of contrast was observed on CT in arthroscopy joints, whereas arthrocentesis controls maintained well-contained intraarticular contrast.
  • Cadaveric CT imaging with 3D segmentation effectively quantified intra- and extracapsular contrast distribution.
  • Dilutional effects (≈64% reduction in intensity) suggest both irrigation fluid residue and tissue diffusion contribute to extravasation.
  • Clinical implication: intraarticular therapeutics (e.g., orthobiologics) may achieve higher effective concentrations if injected later rather than immediately after arthroscopy.

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Multiple Choice Questions on this study

In Rustemeyer 2026 et al., on elbow arthroscopy extravasation, what happened to contrast intensity in the arthroscopy group compared with controls?

A. It increased significantly
B. It decreased significantly
C. It remained unchanged
D. It fluctuated but without significance
E. It became immeasurable

Answer: It decreased significantly

Explanation: Lower Hounsfield unit intensity suggested dilution and spread of contrast into surrounding tissues.
In Rustemeyer 2026 et al., on elbow arthroscopy extravasation, how did the total volume of contrast-enhanced fluid compare between arthroscopy and arthrocentesis groups?

A. It was significantly lower in the arthroscopy group
B. It was significantly higher in the arthroscopy group
C. There was no measurable difference
D. It was higher only at later time points
E. It fluctuated randomly without statistical significance

Answer: It was significantly higher in the arthroscopy group

Explanation: The arthroscopy group showed significantly greater total contrast volume, reflecting leakage into periarticular tissues.
In Rustemeyer 2026 et al., on elbow arthroscopy extravasation, what clinical recommendation was suggested regarding intraarticular therapeutic injections after elbow arthroscopy?

A. Inject higher volumes immediately after surgery
B. Administer injections before arthroscopy
C. Delay injection until a later time point after arthroscopy
D. Perform injections only under fluoroscopy
E. Avoid intraarticular injections entirely

Answer: Delay injection until a later time point after arthroscopy

Explanation: Because arthroscopy portals allow fluid leakage, delaying injection may improve intraarticular retention and therapeutic concentration.
In Rustemeyer 2026 et al., on elbow arthroscopy extravasation, how did contrast volume and intensity change over the 15-minute observation period after injection?

A. Both increased significantly
B. Both decreased significantly
C. They changed significantly only in arthroscopy joints
D. Neither changed significantly over time
E. Volume increased but intensity decreased significantly

Answer: Neither changed significantly over time

Explanation: The study found that the main extravasation occurred immediately after injection, with no significant temporal change during the first 15 minutes.
In Rustemeyer 2026 et al., on elbow arthroscopy extravasation, which imaging modality was used to quantify intra- and periarticular contrast distribution?

A. Radiography
B. Ultrasound
C. Computed tomography with 3D segmentation
D. MRI arthrography
E. Fluoroscopy

Answer: Computed tomography with 3D segmentation

Explanation: The study used serial CT scans with manual 3D segmentation software to measure contrast volume and intensity intra- and extraarticularly.

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