Miraldo et al: Tibial Plateau Leveling Osteotomy Plate Design Influences Interfragmentary Compression: An In Vitro Study
Veterinary and Comparative Orthopaedics and Traumatology 1, 2026

Tibial Plateau Leveling Osteotomy Plate Design Influences Interfragmentary Compression: An In Vitro Study

🔍 Key Findings

  • Biocurve TPLO plate generated the highest and most uniform interfragmentary compression, particularly in the cranial quadrants (Q1: 0.285 MPa; Q2: 0.304 MPa), due to its opposing angled dynamic compression holes.
  • Synthes TPLO plate produced the lowest compression across all quadrants (0.050–0.111 MPa), remaining within the low compression range.
  • Arthrex plate achieved intermediate compression, with high compression in the craniolateral quadrant (Q2: 0.292 MPa) but only moderate compression elsewhere.
  • Plate design significantly affected compression distribution (p < 0.001), confirming that screw hole orientation and plate geometry influence osteotomy compression patterns.
  • Cranial compression (Q1–Q2) was greatest with the Biocurve plate, potentially improving stability against “rock-back” or loss of tibial plateau angle.
  • No significant differences between plates were found in caudal quadrants (Q3–Q4), suggesting plate design primarily affects cranial compression.
  • Pressure-sensitive film analysis allowed quantitative mapping of compression patterns, dividing the osteotomy interface into four quadrants for standardized comparison.
  • Clinical superiority of one plate was not concluded, but findings suggest plate geometry and dynamic compression hole orientation influence mechanical stability during TPLO fixation.

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Miraldo et al: Tibial Plateau Leveling Osteotomy Plate Design Influences Interfragmentary Compression: An In Vitro Study
Veterinary and Comparative Orthopaedics and Traumatology 1, 2026

🔍 Key Findings

  • Biocurve TPLO plate generated the highest and most uniform interfragmentary compression, particularly in the cranial quadrants (Q1: 0.285 MPa; Q2: 0.304 MPa), due to its opposing angled dynamic compression holes.
  • Synthes TPLO plate produced the lowest compression across all quadrants (0.050–0.111 MPa), remaining within the low compression range.
  • Arthrex plate achieved intermediate compression, with high compression in the craniolateral quadrant (Q2: 0.292 MPa) but only moderate compression elsewhere.
  • Plate design significantly affected compression distribution (p < 0.001), confirming that screw hole orientation and plate geometry influence osteotomy compression patterns.
  • Cranial compression (Q1–Q2) was greatest with the Biocurve plate, potentially improving stability against “rock-back” or loss of tibial plateau angle.
  • No significant differences between plates were found in caudal quadrants (Q3–Q4), suggesting plate design primarily affects cranial compression.
  • Pressure-sensitive film analysis allowed quantitative mapping of compression patterns, dividing the osteotomy interface into four quadrants for standardized comparison.
  • Clinical superiority of one plate was not concluded, but findings suggest plate geometry and dynamic compression hole orientation influence mechanical stability during TPLO fixation.

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Multiple Choice Questions on this study

In Miraldo 2026 et al., on TPLO plate compression, what method was used to measure interfragmentary compression at the osteotomy interface?

A. Strain gauges attached to the plate
B. Pressure-sensitive film inserted at the osteotomy interface
C. Load cells attached to the jig
D. Digital force transducers on screws
E. Finite element modeling

Answer: Pressure-sensitive film inserted at the osteotomy interface

Explanation: The study used ultra-low pressure-sensitive film (Prescale) placed at the osteotomy interface to quantify compression distribution.
In Miraldo 2026 et al., on TPLO plate compression, which osteotomy quadrants showed significantly greater compression with the Biocurve plate compared with other plates?

A. Caudomedial and caudolateral quadrants
B. Craniomedial and craniolateral quadrants
C. Only the caudomedial quadrant
D. Only the caudolateral quadrant
E. All quadrants equally

Answer: Craniomedial and craniolateral quadrants

Explanation: The Biocurve plate generated significantly higher compression in the cranial quadrants (Q1 and Q2), exceeding the high compression threshold.
In Miraldo 2026 et al., on TPLO plate compression, which TPLO plate design generated the highest and most uniform interfragmentary compression across quadrants?

A. Synthes 3.5-mm TPLO plate
B. Arthrex 3.5-mm TPLO plate
C. Biocurve 3.5-mm TPLO plate
D. String-of-Pearls TPLO plate
E. Limited contact DCP plate

Answer: Biocurve 3.5-mm TPLO plate

Explanation: The Biocurve plate produced the highest and most uniform compression across quadrants, particularly cranially, due to opposing angled dynamic compression holes.
In Miraldo 2026 et al., on TPLO plate compression, which plate design feature most likely contributed to the higher cranial compression observed with the Biocurve plate?

A. A straight shaft aligned with the tibial axis
B. Single dynamic compression hole
C. Opposing angled dynamic compression screw holes
D. Caudally tilted plate head
E. Longer plate length

Answer: Opposing angled dynamic compression screw holes

Explanation: The Biocurve plate includes two DCU holes angled in opposing directions, creating cranial and axial compression and producing a more uniform distribution.
In Miraldo 2026 et al., on TPLO plate compression, which TPLO plate generated the lowest interfragmentary compression across all quadrants?

A. Biocurve plate
B. Arthrex plate
C. Synthes plate
D. Locking compression plate
E. String-of-Pearls plate

Answer: Synthes plate

Explanation: The Synthes plate produced the lowest compression values in all quadrants (0.050–0.111 MPa), classified as low compression.

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