Your Custom Quiz

In Peng 2025 et al., on topical amikacin gel, what was the lower limit of quantification (LLOQ) for the assay used?

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Correct. The Siemens Syva EMIT Amikacin Assay used in this study had an LLOQ of 2.5 μg/mL【90†Veterinary Surgery†L1-L20】
Incorrect. The correct answer is 2.5 μg/mL.
The Siemens Syva EMIT Amikacin Assay used in this study had an LLOQ of 2.5 μg/mL【90†Veterinary Surgery†L1-L20】

🔍 Key Findings

Objective: Determine if topical 45 mg/mL amikacin in CMC gel leads to systemic absorption in dogs with wounds.

Dogs enrolled: 11 client-owned dogs, with 31 applications of the gel.

Serum findings:

  • Only 5 of 153 samples were above the 2.5 µg/mL quantification limit
  • All values remained <5 µg/mL, the presumed toxicity threshold
  • No correlation was found between dose-related parameters (mg, mg/kg, mg/cm²) and serum amikacin levels

Peak concentrations were observed at ~2 hours post-application, declining rapidly thereafter

No nephrotoxicity observed, and most values were below detection

Conclusion: Topical amikacin gel appears safe at doses up to 24.9 mg/kg, with minimal systemic absorption

Peng

Veterinary Surgery

3

2025

Serum amikacin concentrations in dogs with naturally occurring open wounds treated with topical amikacin in carboxymethylcellulose hydrogel

2025-3-VS-peng2-3

Article Title: Serum amikacin concentrations in dogs with naturally occurring open wounds treated with topical amikacin in carboxymethylcellulose hydrogel

Journal: Veterinary Surgery

In Kang 2022 et al., on 3D scaffold reconstruction, what was one key advantage of using a patient-specific osteotomy guide?

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Correct. The custom guide helped match the bone defect with the scaffold for better stability and alignment.
Incorrect. The correct answer is Improved anatomic fit for scaffold placement.
The custom guide helped match the bone defect with the scaffold for better stability and alignment.

🔍 Key Findings

  • Patient-specific 3D-printed PCL/β-TCP scaffold enabled successful zygomatic arch reconstruction in a dog.
  • Complete surgical resection of a zygomatic parosteal osteosarcoma was achieved, with a 0.3 mm histologically clean margin.
  • Post-op imaging showed progressive tissue ingrowth into the scaffold, with Hounsfield Units increasing from 20.4 to 97.8 over 10 months.
  • No complications (e.g., infection, displacement) or tumor recurrence were noted at 16-month follow-up.
  • Use of a patient-specific osteotomy guide improved anatomical fit and facilitated precise excision and implant placement.
  • Facial symmetry and orbital stability were maintained throughout follow-up.
  • The scaffold remained structurally stable despite limited bone regeneration, suggesting connective tissue filled the defect.
  • Topical mitomycin C was applied intraoperatively for possible anti-neoplastic effect, but efficacy remains unclear.

Kang

Veterinary Surgery

8

2022

Zygomatic arch reconstruction with a patient-specific polycaprolactone beta-tricalcium phosphate scaffold after parosteal osteosarcoma resection in a dog

2022-8-VS-kang-5

Article Title: Zygomatic arch reconstruction with a patient-specific polycaprolactone beta-tricalcium phosphate scaffold after parosteal osteosarcoma resection in a dog

Journal: Veterinary Surgery

In Silveira 2022 et al., on GTO in canine THR, what was the cause of the one reported post-operative complication?

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Correct. Luxation occurred in one dog due to undersized cup/head and soft tissue laxity, not GTO failure.
Incorrect. The correct answer is Post-operative luxation related to soft tissue tension loss.
Luxation occurred in one dog due to undersized cup/head and soft tissue laxity, not GTO failure.

🔍 Key Findings

  • GTO enabled successful cementless THR in dogs with severe medialization of the greater trochanter or chronic craniodorsal hip luxation.
  • All 5 hips had acceptable long-term outcomes (median follow-up: 48 months) with full function and no persistent complications.
  • Only one major complication occurred—a luxation unrelated to the GTO and successfully corrected with cup revision.
  • GTO facilitated femoral canal access and gluteal preservation, reducing risk of iatrogenic injury during broaching.
  • All GTOs healed radiographically (4 by 6 weeks, 1 by 12 weeks), with no cases of nonunion or implant migration.
  • No complications related to GTO or PTBW fixation (pins + tension band) were observed in any dog.
  • Surgical planning included templating both THR and GTO to ensure ideal alignment and reduce fracture risk.
  • GTO may be especially valuable in luxoid hip dysplasia phenotypes or chronically fixed luxations.

Silveira

Veterinary Surgery

2

2022

Greater trochanter osteotomy as a component of cementless total hip replacement: Five cases in four dogs

2022-2-VS-silveira-5

Article Title: Greater trochanter osteotomy as a component of cementless total hip replacement: Five cases in four dogs

Journal: Veterinary Surgery

In Thomsen 2024 et al., on CT accuracy for liver tumors, which phase of contrast-enhanced CT was most helpful in localization?

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Correct. Both were reported as useful in roughly 30–38% of cases.
Incorrect. The correct answer is Both portal and hepatic venous.
Both were reported as useful in roughly 30–38% of cases.

🔍 Key Findings

  • CT localization of liver masses was more accurate by division (88%) than by lobe (74.3%)
  • Inter-radiologist agreement was excellent for division (kappa up to 0.885) and only moderate–good for lobe
  • Quadrate and right lateral lobes had significantly lower localization accuracy compared to left lateral or medial lobes
  • CT localization of the left division was most accurate (90.1%) compared to central (77.1%) and right (88.3%)
  • Portal and hepatic venous phases were equally helpful for localization (each ~30–38% usefulness)
  • No significant associations found between histopathologic diagnosis and localization accuracy
  • Lobe-level CT localization should be interpreted with caution, especially for the quadrate and right lateral lobes
  • Radiologist experience likely influenced accuracy, with the most experienced radiologist performing best

Thomsen

Veterinary Surgery

7

2024

Computed tomography scan accuracy for the prediction of lobe and division of liver tumors by four board-certified radiologists

2024-7-VS-thomsen-3

Article Title: Computed tomography scan accuracy for the prediction of lobe and division of liver tumors by four board-certified radiologists

Journal: Veterinary Surgery

In McLean 2024 et al., which variables were found to have no significant association with rock-back?

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Correct. Neither plate inclination nor ECA were associated with rock-back in this clinical study (p = 0.4 and 0.2):contentReference[oaicite:1]{index=1}
Incorrect. The correct answer is Plate inclination and exit cut angle (ECA).
Neither plate inclination nor ECA were associated with rock-back in this clinical study (p = 0.4 and 0.2):contentReference[oaicite:1]{index=1}

🔍 Key Findings Summary

  • 95 TPLO procedures reviewed retrospectively with follow-up radiographs
  • Rock-back defined as increase in tibial plateau angle (TPA) ≥2° from immediate post-op to recheck
  • 21% of stifles (20/95) experienced rock-back
  • Mean ΔTPA among rock-back cases = 3.2° ± 2.6°
  • No implant failures or tibial tuberosity fractures were reported in these cases
  • Plate inclination and exit cut angle (ECA) were not associated with increased risk of rock-back (p = 0.4 and 0.2)
  • Authors hypothesize that compression across osteotomy in vivo may mitigate torsional effects from ECA, unlike in gap-model studies
  • Emphasizes that rock-back is relatively common, even with well-placed implants

Mclean

Veterinary and Comparative Orthopedics and Traumatology

6

2024

Effect of Plate Inclination and Osteotomy Positioning on Rock-back following Tibial Plateau Levelling Osteotomy in Dogs

2024-6-VCOT-mclean-2

Article Title: Effect of Plate Inclination and Osteotomy Positioning on Rock-back following Tibial Plateau Levelling Osteotomy in Dogs

Journal: Veterinary and Comparative Orthopedics and Traumatology

In Neal 2023 et al., on transcondylar screw placement, what was the observed rate of joint infringement when using the aiming device?

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Correct. Joint infringement occurred in 10% of aiming device cases vs. 1.45% with fluoroscopy (8x risk, p = .0575).
Incorrect. The correct answer is 10%.
Joint infringement occurred in 10% of aiming device cases vs. 1.45% with fluoroscopy (8x risk, p = .0575).

🔍 Key Findings

  • Aiming device provided comparable trajectory accuracy to fluoroscopy, especially in right limbs (1.9° vs. 3.4°, p = .0128).
  • Eccentricity (deviation from condylar center) was lower with fluoroscopy (3.1 mm vs 4.2 mm, p = .0017), making fluoroscopy more precise.
  • Odds of joint infringement were 8× higher with the aiming device, though not statistically significant (p = .0575).
  • Residents had greater screw trajectory deviation than diplomates (p = .0366), highlighting impact of experience.
  • Aiming device procedures took less time than fluoroscopy in some scenarios, particularly for right limbs with right-handed surgeons.
  • Fluoroscopic procedures had more pin/drill attempts, increasing risk of glove puncture and potential aseptic breaks.
  • Mean deviation angles in both groups (<3.5°) were within acceptable range to avoid intracondylar fracture gap.
  • Cadaver model used large-breed, healthy adult dogs, not small-breed immature dogs, limiting generalizability.

Neal

Veterinary Surgery

4

2023

The effect of an aiming device on the accuracy of humeral transcondylar screw placement

2023-4-VS-neal-3

Article Title: The effect of an aiming device on the accuracy of humeral transcondylar screw placement

Journal: Veterinary Surgery

In Ibrahim 2022 et al., on scrotal arterial supply, what was concluded regarding the use of scrotal flaps in neutered dogs?

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Correct. Neutered or cryptorchid dogs may have insufficient scrotal tissue for reliable flap design.
Incorrect. The correct answer is Scrotum may be too small or absent.
Neutered or cryptorchid dogs may have insufficient scrotal tissue for reliable flap design.

🔍 Key Findings

  • Dorsal scrotal arteries, branching from the ventral perineal arteries, are the dominant arterial supply to the scrotum in dogs.
  • The ventral scrotal arteries, arising from the external pudendal arteries, perfused only the cranial scrotal border and were inconsistently present or absent in some dogs.
  • A scrotal flap based on the dorsal scrotal arteries showed strong perfusion and may be a viable axial pattern flap.
  • Perfusion was consistent across fresh and frozen cadavers, showing no difference due to preservation method.
  • Poor flap survival (27%) occurred when based on cranial supply alone (i.e., ventral scrotal arteries), confirming importance of preserving caudal supply.
  • There are anastomoses between dorsal and ventral scrotal arteries, offering collateral flow but insufficient alone for complete perfusion.
  • Scrotal flaps based on the caudal pedicle may be applicable for reconstruction of proximal medial/lateral thigh wounds.
  • Proposed flap requires careful preservation of ventral perineal arteries, ideally designed 2.5–3 cm lateral to midline in large dogs.

Ibrahim

Veterinary Surgery

4

2022

Arterial supply to the scrotum: A cadaveric angiographic study

2022-4-VS-ibrahim-4

Article Title: Arterial supply to the scrotum: A cadaveric angiographic study

Journal: Veterinary Surgery

In Murphy 2024 et al., which breeds had significantly lower odds of contralateral CCLR?

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Correct. Both breeds had significantly lower odds: Labradors (OR 0.58, p=0.007) and Goldens (OR 0.47, p=0.028).
Incorrect. The correct answer is Labrador Retriever and Golden Retriever.
Both breeds had significantly lower odds: Labradors (OR 0.58, p=0.007) and Goldens (OR 0.47, p=0.028).

🔍 Key Findings Summary

  • Prevalence of contralateral CCLR in dogs ≥8 years and ≥15kg was 19.1%, notably lower than previous studies (33–50%).
  • Median time to contralateral CCLR was 12.9 months.
  • Older age reduced risk — 2% decrease per month of age (p=0.003).
  • Golden Retrievers and Labradors had significantly lower risk (p=0.028 and p=0.007, respectively).
  • No effect found from TPA, meniscal injury, or comorbidities (e.g., hip dysplasia, hypothyroidism).

Murphy

Veterinary and Comparative Orthopedics and Traumatology

1

2024

The Prevalence and Risk Factors of Contralateral Cranial Cruciate Ligament Rupture in Medium-to-Large (≥15kg) Breed Dogs 8 Years of Age or Older

2024-1-VCOT-murphy-4

Article Title: The Prevalence and Risk Factors of Contralateral Cranial Cruciate Ligament Rupture in Medium-to-Large (≥15kg) Breed Dogs 8 Years of Age or Older

Journal: Veterinary and Comparative Orthopedics and Traumatology

In Miller 2024 et al., how did rates of revision surgery compare between FFP and staphylectomy?

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Correct. Revision surgery occurred in 7 dogs (FFP: 4, S: 3); the difference was not statistically significant.
Incorrect. The correct answer is FFP had more revisions but not significantly.
Revision surgery occurred in 7 dogs (FFP: 4, S: 3); the difference was not statistically significant.

🔍 Key Findings Summary

  • Sample: 124 dogs (64 S, 60 FFP); French Bulldogs most common (54/124)
  • Pre-op clinical signs: Exercise intolerance (34/124), stertor (22), regurgitation (7), vomiting (12)
  • Operative time (no concurrent procedure): Longer in FFP (75 vs 51 min, p = .02)
  • Anesthetic time: Longer in FFP (111 vs 80 min, p = .02)
  • Anesthetic complications: Similar rates (FFP 50, S 49; p = .30)
  • Post-op regurgitation: 27/124 (S: 17, FFP: 10; p = .18)
  • Post-op aspiration pneumonia: Rare (S: 4, FFP: 5)
  • Major complications: Rare (5/124); 2 dogs euthanized post-op (1 per group)
  • Revision surgery: Needed in 7/124 (3 S, 4 FFP)

Miller

Veterinary Surgery

1

2024

Complications and outcome following staphylectomy and folded flap palatoplasty in dogs with brachycephalic obstructive airway syndrome

2024-1-VS-miller-4

Article Title: Complications and outcome following staphylectomy and folded flap palatoplasty in dogs with brachycephalic obstructive airway syndrome

Journal: Veterinary Surgery

In Buote 2023 et al., on laparoscopic gastrectomy in cats, what was the primary purpose of the cadaveric phase of the study?

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Correct. The cadaver study was used to develop and optimize the laparoscopic approach and stapling protocol before live trials.
Incorrect. The correct answer is To refine the surgical technique and stapler use.
The cadaver study was used to develop and optimize the laparoscopic approach and stapling protocol before live trials.

🔍 Key Findings

  • LVSG was feasible in 9/10 feline cadavers with successful stapled gastrectomy and minimal technical complications.
  • Stenosis at the incisura angularis occurred in 2/10 cadavers, associated with staple placement too close to the lesser curvature.
  • Leak testing was negative in 8 cadavers and both live cats, indicating effective staple sealing.
  • Mean stomach resection was ~28%, though less than human standards (~75–80%) for metabolic effects.
  • Surgery was performed safely in two live feline subjects, with no intraoperative or postoperative complications over a 6-month follow-up.
  • Technique refinements included orogastric tube placement and custom 3D-printed cannulas to improve staple line accuracy and avoid stenosis.
  • Tri-Staple purple cartridges provided graduated compression suited for feline gastric tissue thickness (~2.5 mm).
  • No need for staple line oversew in live cats; staple-only closure proved safe in this short-term study.

Buote

Veterinary Surgery

6

2023

Laparoscopic vertical sleeve gastrectomy in felines: A cadaveric feasibility study and experimental case series in two cats

2023-6-buote2-5

Article Title: Laparoscopic vertical sleeve gastrectomy in felines: A cadaveric feasibility study and experimental case series in two cats

Journal: Veterinary Surgery

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