🔍 Key Findings

• No leakage occurred using pretied ligature loops (PLL) or double-shank (DS) titanium clips up to 40 cm H₂O airway pressure.
• 1/10 stapled lobes leaked at supraphysiologic pressure (40 cm H₂O), but this was not statistically significant (p = .33).
• All techniques sealed effectively under physiologic and supraphysiologic pressures in cadaveric feline lungs.
• PLL and DS clips required less working space than staplers, making them more practical for small thoracic cavities.
• DS titanium clips offer enhanced security due to dual shanks and tissue-gripping design, reducing clip slippage.
• Leak testing was cyclic and submerged, simulating physiologic ventilation and allowing robust evaluation.
• Stapling failure occurred along the staple line, highlighting risks of air leakage due to staple misalignment or poor hilar access.
• PLL and DS clips may be cost-effective and efficient alternatives for open or minimally invasive feline lung lobectomy.

🔍 Key Findings

• A within-animal randomized controlled trial was performed in 32 adult cats undergoing ovariohysterectomy, allowing direct comparison of two intradermal skin-closure patterns in the same incision.
• Each 4-cm ventral midline incision was divided into cranial and caudal halves, randomly assigned to either a modified Allgower-Donati (mAD) intradermal pattern or a standard intradermal horizontal mattress pattern (SP).
• The modified Allgower-Donati pattern significantly increased wound-edge perfusion, whereas the standard intradermal horizontal mattress pattern decreased perfusion.
• Mean perfusion change was +59.7 ± 124.1 BPU with mAD versus −20.2 ± 119.9 BPU with SP (p < .01), demonstrating improved acute microcirculation with the mAD technique.
• Relative perfusion increased by 115.3% with mAD but decreased by 24.1% with SP, reinforcing the perfusion advantage of the modified pattern.
• The critical technical difference was suture bite orientation: mAD placed dermal bites perpendicular (90°) to the incision, while the standard pattern placed bites parallel and close to the wound edge.
• Both techniques used buried continuous intradermal closure with 4-0 poliglecaprone, maintaining the cosmetic and patient-comfort advantages of intradermal suturing.
• No incisional complications were reported within 30 days, although follow-up relied on re-presentation rather than scheduled examination, limiting detection of minor complications.

🔍 Key Findings

• MEFF occurred in 11.4% (10/88 elbows) following medial-to-lateral transcondylar screw placement in dogs with HIF.
• Screw size to condylar height ratio >41% significantly increased MEFF risk (P = .004, OR 1.52).
• MEFF was not recognized intraoperatively in 60% of cases and was only seen on follow-up or retrospective imaging review.
• Screw loosening was the most common complication (11.2%), observed both with and without MEFF.
• MEFF tended to increase the risk of screw loosening (P = .06), but was not statistically significant.
• Most MEFFs did not require treatment and healed radiographically by 14–17 weeks in monitored cases.
• Shaft screws were used in all MEFF cases, but shaft vs cortical design was not significantly associated with MEFF.
• The clinical impact of MEFF was minor in most cases, although long-term significance is unknown.

🔍 Key Findings Summary

• Subjects: 12 healthy colony cats, 68 total liver samples collected via laparoscopy
• Biopsy instruments: 3 mm vs 5 mm Storz Blakesley cup forceps
• Techniques: Twist (T), Pull (P), Twist + Pull (TP)
• Results:
  • 5 mm forceps yielded significantly more hepatic lobules (mean 12.4 vs 4.9), portal triads (29.6 vs 19.0), weight, and histologic area (p < .01)
  • T and P techniques yielded more portal triads and lobules than TP (p = .003 and p = .015)
  • TP technique resulted in greater tissue crush vs T (p = .01)
  • Good diagnostic agreement between 3 mm and 5 mm samples only with TP (κ = 0.75)
  • All samples were of sufficient diagnostic quality, despite size or technique
• Clinical implication: Both 3 mm and 5 mm forceps are viable; further studies are needed to confirm diagnostic accuracy of 3 mm samples

🔍 Key Findings

• Chlorhexidine-based asepsis protocols were comparable to povidone-iodine for reducing surgical site infection (SSI) rates in veterinary surgery.
• No significant difference in skin bacterial colonization was observed between the two antiseptics, at both immediate and delayed timepoints.
• Chlorhexidine-alcohol protocols showed a non-significant trend toward improved bacterial reduction in some studies, though inconsistent across all studies.
• Use of neutralizing agents was inconsistent, which may have led to overestimation of antiseptic efficacy in several studies.
• Formulations and concentrations varied widely (e.g., chlorhexidine 0.5–4%, povidone-iodine 0.7–1%), contributing to heterogeneity and limiting definitive conclusions.
• Only a minority of studies reported using CDC criteria for SSI diagnosis, affecting the reliability of infection outcomes.
• Risk of bias was high or unclear in multiple domains across all included studies, limiting overall confidence in conclusions.
• Meta-analysis confirmed no statistically significant superiority of either protocol for SSI prevention or skin bacterial reduction.

🔍 Key Findings

• Primary repair of NSAID-associated full-thickness gastroduodenal ulcers was successful in 73% (8/11) of cases.
• NSAID overdose, concurrent corticosteroid use, or extended duration were identified in 9/11 dogs and were major contributors to ulceration.
• All perforations were in the pylorus or proximal duodenum, locations suitable for primary closure.
• No significant association between ulcer size or location and postoperative survival.
• Preoperative hyperlactatemia trended toward increased mortality (P = .0544; OR 2.045).
• Postoperative vasopressor use was linked with a 9-fold increased risk of mortality (P = .0545).
• Dehiscence was rare, suspected in only 1 of 11 cases, indicating that primary repair is structurally sound in selected cases.
• Median follow-up of 444 days showed long-term survival was achievable post-primary repair.

🔍 Key Findings

• Each PLC significantly increased passive range of motion (ROM) in the sagittal and dorsal planes (p < .05).
• No significant change was observed in rotational ROM after either PLC.
• First PLC increased sagittal ROM by 2.4° (23% increase); second PLC added 1.0° (8% increase).
• Dorsal ROM increased by 2.3° after first PLC and 1.5° after second PLC.
• Second PLC did not cause greater destabilization than the first — both contributed similarly to ROM increase.
• Failure testing showed that spinal segments with two PLCs failed at 13 Nm, while native spines withstood up to 25 Nm, suggesting reduced load-bearing capacity but not clinically significant under normal conditions.
• Rotational stability was preserved, possibly due to intact facet joints and lamina, which play a larger role in rotation.
• Study supports the clinical feasibility of two consecutive PLCs, but cautions against excessive bone removal due to potential for spinal instability.

🔍 Key Findings

• No significant difference in peak load, failure load, stiffness, or 3 mm gap formation among bone tunnel types.
• Transverse tunnel (TT) constructs had 25% higher yield load than modified tunnels (MT) (P = .027).
• Most common failure mode was suture pull-through (67%), with no significant difference between groups.
• Gap formation ≥3 mm occurred in ~90% of constructs; no significant difference in force needed for gap among groups.
• All bone tunnel techniques (TT, VT, MT) are viable options for CCT reattachment in dogs.
• The 3-loop pulley (3LP) pattern provided strong, uniform repair, with higher loads to failure than previously reported.
• TT constructs showed more tendon distortion at the repair interface during loading.
• Inclusion of accessory tendon may have improved repair strength compared to prior studies using GT alone.

🔍 Key Findings

Study Design: Case series of 8 dogs with confirmed or suspected PJI after total hip replacement (THR)
Dogs were categorized into:

• Curative intent (CI) group (n=5): short-duration infections, implant retention attempted
• Non-curative intent (NCI) group (n=3): chronic infections, implants scheduled for removal or revision

Success Rate: 7 of 8 dogs had infection resolution, including 4 of 5 in the CI group
Sampling sensitivity:

• Arthroscopic culture success was 80% in the CI group but only 33% in the NCI group
• All explanted implants from NCI group yielded positive cultures

Common isolates: Staphylococcus pseudointermedius (including MRSP), S. epidermidis, Stenotrophomonas maltophilia, and E. coli
Ancillary treatments included:

• Partial synovectomy, high-volume lavage (5–10 L), biofilm-depleting lavage, and/or amikacin-impregnated calcium sulfate beads

Mean follow-up: >1 year (mean 812 days); no signs of recurrence in successfully treated cases
Conclusions: Arthroscopic management of THR infections is feasible and effective in appropriately selected dogs. Success aligns with human literature when infection type is favorable (Type 1, 3, 4). Sensitivity of arthroscopic culture is higher in early/acute infections.

🔍 Key Findings

• Local recurrence occurred in 17.8% of dogs, and was associated with significantly decreased survival (551 vs 1722 days, p = .0038).
• Lymph node metastasis occurred in 26.7% of dogs and was significantly associated with shorter disease-free interval (194 vs not reached, p = .0012) and lower survival (551 vs 1722 days, p = .043).
• Mitotic index >7 was significantly associated with higher recurrence (80% vs 22.5%, p = .02), shorter DFI (139 vs not reached days, p < .001), and shorter survival (247 vs 1722 days, p = .05).
• Infiltrative growth pattern was associated with shorter DFI (268 vs 1864 days, p = .011), but not with survival or recurrence.
• Incomplete margins (≤1 mm) were not significantly associated with recurrence (p = .085), but did correlate with shorter DFI (p = .043).
• Chemotherapy or radiation therapy was associated with shorter DFI and survival, likely due to selection bias for more aggressive disease.
• Tumor size >3 cm was associated with decreased survival (p = .031), but not with recurrence or DFI.
• Multinucleation and necrosis were not associated with prognosis outcomes.