🔍 Key Findings

• Neonatal survival to discharge was 93.1% overall, with no significant difference between brachycephalic (94.8%) and nonbrachycephalic (91.8%) breeds.
• Elective C-section significantly improved neonatal survival (99.2%) compared to emergency C-section (87.1%) (p < .001).
• Larger C-section litter size was positively associated with survival (p = .004; OR 1.57), whereas total litter size had no effect.
• Maternal heart rate and stage of labor were associated with neonatal mortality in univariable analysis, but not multivariable.
• Brachycephalism alone was not a risk factor for neonatal mortality (p = .221) in multivariable analysis.
• Emergency C-section was the strongest predictor of neonatal mortality (OR 4.75), regardless of breed.
• Multidisciplinary team approach likely contributed to high survival rates, emphasizing importance of coordinated care.
• Historical factors such as primiparity and maternal age were not associated with mortality in this cohort.

🔍 Key Findings

Source: Bush et al., 2023, Veterinary Surgery

• Median survival time (MST) after surgery was 1886 days, which is significantly longer than previously reported.
• Lymph node metastasis at surgery was a negative prognostic factor, reducing MST to 248 days (vs. 2340 days without nodal involvement).
• Local recurrence occurred in 42% of dogs, with a median disease-free interval (DFI) of 191 days.
• Metastatic disease occurred in 32% of dogs, most commonly to the lungs, with a median DFI of 299 days.
• Histologic features (e.g., margin status, capsular, lymphatic, or vascular invasion) were not significantly correlated with recurrence or metastasis.
• Facial nerve injury occurred in 9.7% perioperatively, especially after parotidectomy; intraoperative facial nerve transection led to long-term deficits.
• Adjuvant therapies (chemotherapy, radiation, NSAIDs) did not significantly affect survival time.
• Incisional biopsy was only 38% concordant with final excisional histology, suggesting limited reliability for definitive diagnosis.

🔍 Key Findings

• Routine follow-up radiographs after MPL surgery influenced management in only 3% of asymptomatic cases.
• Isolated radiographic abnormalities were rare (3.3%) and even less likely to alter treatment unless accompanied by clinical concerns.
• Dogs with both radiographic changes and clinical/owner concerns had 32× higher odds of a management change (OR 32.16, P < .001).
• Lameness, NSAID use, or prior unplanned visits significantly increased the odds of altered post-op plans.
• Owner-reported concerns alone led to a change in only 1.6% of cases without corroborating clinical findings.
• Radiographic follow-up was deemed unnecessary in dogs without owner concerns or abnormal physical findings.
• Hands-on clinical exam remains critical, though video-based rechecks may aid triage in uncomplicated cases.
• The study supports selective radiographic follow-up, reducing unnecessary imaging, stress, and clinician workload.

🔍 Key Findings

Mortality rate: 36% (12/33)
Cholecystectomy performed: 94% of dogs (31/33)
New significant prognostic factors for survival:

• Hyperbilirubinemia (p = .049) — threshold = 60.5 μmol/L
• Use of vasopressors (p = .002)
• Renal dysfunction postoperatively (p = .008)
• Number of postoperative complications (p = .005)

Multivariate model: Total bilirubin and number of complications best predicted survival
Septic vs nonseptic effusion: No significant difference in survival
Diagnostic imaging: Ultrasound sensitivity for extrahepatic biliary rupture = 38%
Most cultured pathogen: E. coli (80% of septic cases)

🔍 Key Findings

PL-30 group (partial, TA30-V3 wedge):

• 100% leaked
• Median leakage pressure: 10 cm H₂O
• Most failures from periphery of staple line

PL-60 group (partial, TA60-3.5):

• 100% leaked
• Median leakage pressure: 18 cm H₂O
• Better than PL-30 (p = .006)

TL-30 group (total, TA30-V3):

• Only 1 of 11 leaked (at 22 cm H₂O)
• All others resisted pressures >50–65 cm H₂O
• Significantly higher leakage pressure than both PL groups (p < .001)

Odds ratios (leakage vs TL-30):

• PL-30: OR 437 at both 20 and 30 cm H₂O (p = .003)
• PL-60: OR 437 at 20 cm H₂O and 133 at 30 cm H₂O (p = .003)

Recommendation: Prefer TL-30 when possible. If partial needed, PL-60 superior to PL-30, but all partials leaked at physiologic pressures.

🔍 Key Findings

• Study population: 116 dogs underwent cementless THR; grouped by age:
  • Group A: ≤6 months (n = 27)
  • Group B: >6 to ≤12 months (n = 41)
  • Group C: >12 months (n = 48)
• Overall perioperative complication rate: 31.9% (37/116)
  • Group A: 22.2%
  • Group B: 26.8%
  • Group C: 41.7%
• No significant difference in total complication rate by age (p = .207), though older dogs (Group C) had numerically higher rates.
• Luxation was significantly more common in dogs >12 months:
  • Group C: 14.6% vs. Group A (0%) and Group B (2.4%) → p = .049
• Most common complications: luxation (9.5%) and intraoperative fissure or fracture (9.5%)
• Time under anesthesia and surgery duration were not associated with complication risk (p = .297 and p = .781)
• No infections or aseptic loosening observed during the 8-week follow-up.

🔍 Key Findings

• Dogs with two or three congenital extrahepatic portosystemic shunts (M-EHPSS) had outcomes comparable to dogs with single EHPSS when all shunts were appropriately identified and attenuated.
• Miniature Schnauzers comprised 47% (7/15) of cases, suggesting a potential breed predisposition to M-EHPSS.
• The left gastrophrenic–left gastroazygos (LGP–LGA) combination was the most common shunt configuration (67%).
• Left gastrophrenic shunts were consistently the shunts most commonly missed during initial CT interpretation, resulting in incomplete attenuation in five dogs.
• Good or excellent long-term outcomes occurred in 86% (12/14) of treated dogs despite some dogs having incomplete attenuation.
• Only one postoperative mortality occurred (7%), secondary to post-attenuation neurologic syndrome (PANS).
• Dogs with missed shunts showed less improvement in bile acids than dogs with complete attenuation, emphasizing meticulous CT evaluation before surgery.
• Clinical presentation and biochemical abnormalities closely resembled those of dogs with single congenital EHPSS rather than representing a more severe disease.

🔍 Key Findings

• Short working length constructs had significantly higher stiffness and lower strain than long constructs in compression bending (p = 0.0172).
• In tension bending, short constructs also had higher precontact stiffness and lower strain, but this reversed after transcortical contact (~150 N).
• Transcortical contact increased stiffness only in long constructs, producing a bilinear load-displacement curve.
• Postcontact stiffness was higher in long constructs, but this may not reflect clinical benefit due to risks of high interfragmentary strain.
• Short working length reduced strain at multiple ROIs under both loading conditions, including over fracture gap (Tables 1–3).
• Increased working length promoted stress concentration and deformation, especially in compression bending.
• In vitro benefits of long constructs (via contact stability) may not translate to healing, as repetitive loading could increase plate strain and bone resorption.
• Plate strain was effectively mapped using 3D digital image correlation, confirming regional strain differences between configurations.

🔍 Key Findings

• CPAP at 5 cmH₂O via helmet significantly improved PaO₂/FiO₂ ratio in the early postoperative period of brachycephalic dogs, supporting enhanced pulmonary oxygen exchange (p = .04).
• CPAP had no significant effect on SpO₂ (p = .9), PaCO₂ (p = .18), or rectal temperature (p = .5).
• Helmet tolerance decreased over time, with 13 dogs withdrawn for intolerance (9 CPAP, 4 control) and 6 dogs withdrawn for airway compromise (5 control, 1 CPAP).
• CPAP group maintained PaO₂/FiO₂ ratios near or above 400 mmHg, while control dogs showed consistently lower values.
• Authors suggest PaO₂/FiO₂ is a more reliable oxygenation measure than SpO₂ for evaluating postoperative lung function.
• The study found no cases of hyperthermia; temperatures normalized over time in both groups.
• Arterial catheterization failed in several dogs, limiting blood gas analysis to a subset of the population.
• Authors recommend further studies focused on BOAS patients and exploring longer-duration CPAP use to assess impact on critical outcomes like tracheostomy rates or hospitalization.

🔍 Key Findings

• 2.4 mm LCP with a 1.6 mm IM pin had the highest axial stiffness and yield strength among the tested constructs.
• Axial stiffness was significantly higher in the 2.4 mm LCP + 1.6 mm IM pin group compared to 2.7 mm LCP alone (p = .013).
• No significant difference in torsional stiffness was found among groups.
• 2.4 mm LCP + 1.0 mm pin had the lowest stiffness and failure load, underperforming both other constructs.
• All constructs failed via valgus bending, consistent with clinical observations in feline tibial fractures.
• A 1.6 mm pin (~50% canal fill) resulted in superior construct performance vs. 1.0 mm (~30% fill).
• Group 2 (2.4 LCP + 1.6 mm pin) outperformed the 2.7 mm LCP alone in stiffness, despite using a smaller plate.
• Plate–rod constructs may better preserve periosteal blood supply and support minimally invasive stabilization strategies.