🔍 Key Findings

• Bending tees significantly increased mediolateral bending stiffness, but not craniocaudal stiffness, in plate-bone constructs.
• Mean mediolateral stiffness was 43.2 N/mm with tees vs. 41.1 N/mm without (p = 0.0042), though the absolute difference was small.
• No significant differences were found in craniocaudal bending stiffness between constructs with or without tees (p = 0.89).
• Plastic deformation occurred in all constructs; no screw pull-out or implant breakage was observed.
• SOP nodes may resist compressive but not tensile deformation, suggesting variable mechanical contributions depending on loading direction.
• Craniocaudal bending had greater stiffness than mediolateral due to higher area moment of inertia along the node diameter.
• Clinical relevance of added stiffness from tees remains unclear, warranting further in vivo and cyclic testing.
• This was the first study to directly test SOP constructs with/without tees over a fracture gap in multiple planes.

🔍 Key Findings

• Double-loop cerclage resisted the highest peak load (805 N) and maintained tension longer than twist (488 N) and single-loop (397 N) configurations.
• Double-loop cerclage sustained 500,000 cycles at 60–80% of peak load in some cases without loosening, outperforming other types.
• Twist knots loosened rapidly, often within 10 cycles even at low loads (100–390 N).
• Single-loop knots performed better than twist, with partial resistance up to 100,000 cycles at 160 N, but showed wide variability.
• All loosening occurred before wire breakage, indicating clinical failure would happen from slack, not fracture.
• Double-loop cerclage had highest initial tension (323 N) compared to single-loop (124 N) and twist (69 N).
• Fatigue limit was not identified for twist, since they all loosened early at even 20% of peak load.
• Clinical recommendation: double-loop cerclage is best for resisting repeated subfailure loading, ideal for fissure prevention or fragment stabilization.

🔍 Key Findings

40 dogs underwent splenectomy using 16 bipolar vessel sealing devices (VSDs)
Devices were reused up to 4 times after handwashing and ethylene oxide (EtO) sterilization
Biologic debris was found in 100% of devices, specifically under the transection blade, even after a single use

• Mostly scant (14/16) or mild (2/16) debris

No devices or debris yielded positive aerobic culture after EtO sterilization
EtO sterilization proved microbiologically effective despite visible residue
Perioperative failure rate: 1 device (malfunctioned during first activation)

🔍 Key Findings

• LVSG was feasible in 9/10 feline cadavers with successful stapled gastrectomy and minimal technical complications.
• Stenosis at the incisura angularis occurred in 2/10 cadavers, associated with staple placement too close to the lesser curvature.
• Leak testing was negative in 8 cadavers and both live cats, indicating effective staple sealing.
• Mean stomach resection was ~28%, though less than human standards (~75–80%) for metabolic effects.
• Surgery was performed safely in two live feline subjects, with no intraoperative or postoperative complications over a 6-month follow-up.
• Technique refinements included orogastric tube placement and custom 3D-printed cannulas to improve staple line accuracy and avoid stenosis.
• Tri-Staple purple cartridges provided graduated compression suited for feline gastric tissue thickness (~2.5 mm).
• No need for staple line oversew in live cats; staple-only closure proved safe in this short-term study.

🔍 Key Findings

• Adding a single locking throw significantly increased holding security for specific knots, including the surgeon's throw (p = .0001) and square throw (p = .0002).
• For the Miller's throw (p = .166) and strangle throw (p = .808), no significant improvement was observed with a locking throw.
• After locking throw addition, all five knots leaked at similar pressures (p = .5233), and these pressures exceeded physiologic arterial pressures.
• Surgeon's throw without a locking throw had the lowest leak pressure (62.5 ± 46.2 mm Hg), below physiologic arterial values.
• The square throw without locking also leaked below physiologic pressures (148.7 ± 109.4 mm Hg), though it outperformed the surgeon's throw.
• Miller’s and strangle throws performed significantly better than square or surgeon’s throws without locking, achieving leak pressures >200 mm Hg.
• All knots used 2-0 polyglyconate monofilament (Maxon); no comparisons across suture types or sizes were performed.
• Authors concluded that correct tensioning and locking throw addition are key to safe vascular ligation. Miller’s, strangle, or slip knots are preferred for challenging surgical fields.

🔍 Key Findings Summary

• Primary 3.5-mm LCP used with short (SWL), medium (MWL), and long (LWL) working lengths
• Addition of orthogonal 2.7-mm LCP resulted in:
  • Significantly higher bending stiffness for SWL, MWL, and LWL (p < 0.0001)
  • Higher torsional stiffness for MWL and LWL (not for SWL)
  • Significantly lower strain across all working lengths in bending (p < 0.01)
• Working length inversely related to construct stiffness and directly to plate strain
• Orthogonal plates eliminated stiffness differences across working lengths in bending
• Suggests orthogonal plates can improve implant fatigue life and allow compensation when short working lengths are unachievable

🔍 Key Findings

• 12-hole LCPs (80% plate–bone ratio) showed significantly higher construct stiffness than 6-, 8-, or 10-hole plates in both compression and tension bending.
• Strain on the plate was significantly lower in 12-hole vs 6-hole plates at all regions of interest (ROIs), especially around the fracture gap.
• No incremental increases in stiffness or decreases in strain were observed between 6-, 8-, and 10-hole plates—only when comparing to 12-hole plates.
• Bone model strain adjacent to the plate end was significantly lower for 10- and 12-hole plates vs 6-hole plates under both loading conditions.
• The threshold effect suggests biomechanical benefits only emerge beyond a plate–bone ratio of ~80%.
• Working length increased from 9.4 mm (6-hole) to 13 mm (others), potentially influencing strain/stiffness differences.
• Four-point bending was used, as it replicates the most biomechanically relevant force on plated long bones.
• Clinical implication: Longer plates may reduce plate strain and peri-implant bone strain, potentially lowering risk of fatigue failure or stress risers.

🔍 Key Findings

• Adding Locking Head Inserts (LHI) to a 3.5-mm LCP had no effect on plate strain, stiffness, or deformation in an open fracture gap model.
• Peak strain consistently occurred at the Combi-hole over the fracture gap, with values up to ~1837 µε.
• No significant difference in strain was found across configurations with 0, 3, or 9 LHI (p = 0.847).
• Construct stiffness and compressive displacement also remained unchanged regardless of LHI count (p = 0.311 and 0.069 respectively).
• Study contradicted the hypothesis that LHI would reduce strain and increase stiffness under biologic loading.
• Combi-hole design may limit the efficacy of LHI, as LHI only fill the locking portion, not the compression side where strain peaks.
• Implant fatigue risk remains highest over unfilled screw holes, especially over fracture sites—confirming previous failure patterns.
• Surgeons should consider alternative methods to reduce strain when facing high implant load scenarios.

🔍 Key Findings

• Short working length constructs had significantly higher stiffness and lower strain than long constructs in compression bending (p = 0.0172).
• In tension bending, short constructs also had higher precontact stiffness and lower strain, but this reversed after transcortical contact (~150 N).
• Transcortical contact increased stiffness only in long constructs, producing a bilinear load-displacement curve.
• Postcontact stiffness was higher in long constructs, but this may not reflect clinical benefit due to risks of high interfragmentary strain.
• Short working length reduced strain at multiple ROIs under both loading conditions, including over fracture gap (Tables 1–3).
• Increased working length promoted stress concentration and deformation, especially in compression bending.
• In vitro benefits of long constructs (via contact stability) may not translate to healing, as repetitive loading could increase plate strain and bone resorption.
• Plate strain was effectively mapped using 3D digital image correlation, confirming regional strain differences between configurations.

🔍 Key Findings

• Adding Locking Head Inserts (LHI) to a 3.5-mm LCP had no effect on plate strain, stiffness, or deformation in an open fracture gap model.
• Peak strain consistently occurred at the Combi-hole over the fracture gap, with values up to ~1837 µε.
• No significant difference in strain was found across configurations with 0, 3, or 9 LHI (p = 0.847).
• Construct stiffness and compressive displacement also remained unchanged regardless of LHI count (p = 0.311 and 0.069 respectively).
• Study contradicted the hypothesis that LHI would reduce strain and increase stiffness under biologic loading.
• Combi-hole design may limit the efficacy of LHI, as LHI only fill the locking portion, not the compression side where strain peaks.
• Implant fatigue risk remains highest over unfilled screw holes, especially over fracture sites—confirming previous failure patterns.
• Surgeons should consider alternative methods to reduce strain when facing high implant load scenarios.