🔍 Key Findings Summary

• IMN provides relative stability, resists bending/torsion due to central axis alignment
• Larger diameter nails = exponentially greater stiffness (∝ D⁴)
• Trade-off: Larger interlocking holes weaken fatigue strength of the nail
• Reaming increases contact/stability but has pros/cons:
  • Improves outcomes in closed fractures
  • May reduce endosteal blood flow in thin-walled bones (e.g., cats)
• Design advances:
  • Angle-stable IMN reduce rotational slack
  • Expandable nails simplify insertion but may compromise removal or compressive load resistance
  • Precontoured nails match bone curvature but lack consistent clinical superiority
• Material debates continue (e.g., titanium vs. stainless steel vs. magnesium)

🔍 Key Findings

• Patient-specific 3D-printed PCL/β-TCP scaffold enabled successful zygomatic arch reconstruction in a dog.
• Complete surgical resection of a zygomatic parosteal osteosarcoma was achieved, with a 0.3 mm histologically clean margin.
• Post-op imaging showed progressive tissue ingrowth into the scaffold, with Hounsfield Units increasing from 20.4 to 97.8 over 10 months.
• No complications (e.g., infection, displacement) or tumor recurrence were noted at 16-month follow-up.
• Use of a patient-specific osteotomy guide improved anatomical fit and facilitated precise excision and implant placement.
• Facial symmetry and orbital stability were maintained throughout follow-up.
• The scaffold remained structurally stable despite limited bone regeneration, suggesting connective tissue filled the defect.
• Topical mitomycin C was applied intraoperatively for possible anti-neoplastic effect, but efficacy remains unclear.

🔍 Key Findings

• In an ex vivo study of 20 canine femur pairs, implantation of a novel hip resurfacing arthroplasty (HRA) prosthesis reduced maximum load (ML) by 22% and load at collapse (LC) by 27% vs. intact controls (p ≤ 0.05).
• Displacement at maximum load (DML), displacement at collapse (DC), and stiffness (k) were not significantly different between prosthesis and control groups.
• Both groups showed similar failure patterns, with 92% failing at the femoral neck.
• All prosthetic femurs still withstood ~6.2× body weight — exceeding estimated in vivo peak loads (~1.64× BW).
• Prosthesis positioning (neutral vs valgus) had no significant effect on biomechanical outcomes.
• Implant design preserved more metaphyseal bone stock than total hip replacement, possibly explaining the smaller load reduction compared to other short-stem prostheses.
• The press-fit cobalt–chromium design with conical stem allowed full contact and stress distribution over the femoral head/neck.
• Authors conclude the device has adequate immediate biomechanical strength for clinical use, though long-term in vivo studies are needed.

🔍 Key Findings Summary

• IMN provides relative stability, resists bending/torsion due to central axis alignment
• Larger diameter nails = exponentially greater stiffness (∝ D⁴)
• Trade-off: Larger interlocking holes weaken fatigue strength of the nail
• Reaming increases contact/stability but has pros/cons:
  • Improves outcomes in closed fractures
  • May reduce endosteal blood flow in thin-walled bones (e.g., cats)
• Design advances:
  • Angle-stable IMN reduce rotational slack
  • Expandable nails simplify insertion but may compromise removal or compressive load resistance
  • Precontoured nails match bone curvature but lack consistent clinical superiority
• Material debates continue (e.g., titanium vs. stainless steel vs. magnesium)

🔍 Key Findings

• 2.4 mm LCP with a 1.6 mm IM pin had the highest axial stiffness and yield strength among the tested constructs.
• Axial stiffness was significantly higher in the 2.4 mm LCP + 1.6 mm IM pin group compared to 2.7 mm LCP alone (p = .013).
• No significant difference in torsional stiffness was found among groups.
• 2.4 mm LCP + 1.0 mm pin had the lowest stiffness and failure load, underperforming both other constructs.
• All constructs failed via valgus bending, consistent with clinical observations in feline tibial fractures.
• A 1.6 mm pin (~50% canal fill) resulted in superior construct performance vs. 1.0 mm (~30% fill).
• Group 2 (2.4 LCP + 1.6 mm pin) outperformed the 2.7 mm LCP alone in stiffness, despite using a smaller plate.
• Plate–rod constructs may better preserve periosteal blood supply and support minimally invasive stabilization strategies.

🔍 Key Findings

Incidence of BFX lateral bolt stem breakage: 2.95% (13 dogs, 14 stems)

Implant factors:

• 13/14 were BFX lateral bolt stems (sizes #5–7)
• +9 necks used in 5/11 of 17 mm heads
• 10/14 stems undersized based on radiographs
• 10/13 dogs exceeded weight limits for implanted stem size

Malalignment:

• 10/14 had varus alignment (median 3.9°)
• 8/14 had insufficient proximodistal seating

Breakage site: Proximolateral shoulder in all cases

Revision outcomes:

• 11 revised (7 CFX, 3 larger BFX, 1 collared)
• 9/10 revised dogs regained full function
• Complications: 1 rebreakage, 1 periprosthetic fracture, 1 fixation failure

Histopathology:

• Electron microscopy showed fatigue striations and incomplete bead fusion

Conclusion: Avoid small BFX lateral bolt stems if undersized or if long necks required; use weight guidelines to prevent fatigue failure.

🔍 Key Findings

• 12-hole LCPs (80% plate–bone ratio) showed significantly higher construct stiffness than 6-, 8-, or 10-hole plates in both compression and tension bending.
• Strain on the plate was significantly lower in 12-hole vs 6-hole plates at all regions of interest (ROIs), especially around the fracture gap.
• No incremental increases in stiffness or decreases in strain were observed between 6-, 8-, and 10-hole plates—only when comparing to 12-hole plates.
• Bone model strain adjacent to the plate end was significantly lower for 10- and 12-hole plates vs 6-hole plates under both loading conditions.
• The threshold effect suggests biomechanical benefits only emerge beyond a plate–bone ratio of ~80%.
• Working length increased from 9.4 mm (6-hole) to 13 mm (others), potentially influencing strain/stiffness differences.
• Four-point bending was used, as it replicates the most biomechanically relevant force on plated long bones.
• Clinical implication: Longer plates may reduce plate strain and peri-implant bone strain, potentially lowering risk of fatigue failure or stress risers.

🔍 Key Findings Summary

• Primary 3.5-mm LCP used with short (SWL), medium (MWL), and long (LWL) working lengths
• Addition of orthogonal 2.7-mm LCP resulted in:
  • Significantly higher bending stiffness for SWL, MWL, and LWL (p < 0.0001)
  • Higher torsional stiffness for MWL and LWL (not for SWL)
  • Significantly lower strain across all working lengths in bending (p < 0.01)
• Working length inversely related to construct stiffness and directly to plate strain
• Orthogonal plates eliminated stiffness differences across working lengths in bending
• Suggests orthogonal plates can improve implant fatigue life and allow compensation when short working lengths are unachievable

🔍 Key Findings

• Total complication rate was 16.7%, with 5/30 hips experiencing major complications, mostly related to the femoral component.
• Cup-associated complications were rare (3.3%), with only one case of acetabular cup luxation attributed to surgical technique rather than implant failure.
• No cases of late aseptic loosening were observed during a median follow-up of 17.5 months.
• Implant stability was attributed to the SCSL's porous, trabecular titanium surface, enhancing osseointegration.
• Three femoral stem fractures occurred in a single dog, leading to implant removal; material testing was not performed.
• Most complications were femoral in origin (6/7), not acetabular, suggesting improved performance of the SCSL.
• Explantation rate was 13% (4/30), but some removals were due to owner preference against revision.
• Subjective functional outcome was full recovery in 26/30 hips, including one with successful revision of stem subsidence.

🔍 Key Findings

• Adding Locking Head Inserts (LHI) to a 3.5-mm LCP had no effect on plate strain, stiffness, or deformation in an open fracture gap model.
• Peak strain consistently occurred at the Combi-hole over the fracture gap, with values up to ~1837 µε.
• No significant difference in strain was found across configurations with 0, 3, or 9 LHI (p = 0.847).
• Construct stiffness and compressive displacement also remained unchanged regardless of LHI count (p = 0.311 and 0.069 respectively).
• Study contradicted the hypothesis that LHI would reduce strain and increase stiffness under biologic loading.
• Combi-hole design may limit the efficacy of LHI, as LHI only fill the locking portion, not the compression side where strain peaks.
• Implant fatigue risk remains highest over unfilled screw holes, especially over fracture sites—confirming previous failure patterns.
• Surgeons should consider alternative methods to reduce strain when facing high implant load scenarios.