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Griffin et al: Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Veterinary Surgery 1, 2025

🔍 Key Findings

  • Case: 9-year-old Labrador with a right caudal pulmonary adenocarcinoma.
  • Technique: Peritumoral injection of indocyanine green (ICG) under VATS guidance, followed by near-infrared (NIR) imaging.
  • SLN identified: Right tracheobronchial lymph node fluoresced and was safely extirpated.
  • Histology: Grade 1 adenocarcinoma, pneumonia, reactive node.
  • Outcome: Patient deteriorated and died on postoperative day 3 due to systemic complications (not linked to surgical technique).
  • Clinical relevance: First clinical application of SLN mapping for canine pulmonary neoplasia; method feasible with open or minimally invasive approaches.
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog

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← Articles

Griffin et al: Intraoperative sentinel lymph node mapping with indocyanine green via video‐assisted thoracoscopic surgery for primary pulmonary neoplasia in a dog
Veterinary Surgery 1, 2025

🔍 Key Findings

  • Case: 9-year-old Labrador with a right caudal pulmonary adenocarcinoma.
  • Technique: Peritumoral injection of indocyanine green (ICG) under VATS guidance, followed by near-infrared (NIR) imaging.
  • SLN identified: Right tracheobronchial lymph node fluoresced and was safely extirpated.
  • Histology: Grade 1 adenocarcinoma, pneumonia, reactive node.
  • Outcome: Patient deteriorated and died on postoperative day 3 due to systemic complications (not linked to surgical technique).
  • Clinical relevance: First clinical application of SLN mapping for canine pulmonary neoplasia; method feasible with open or minimally invasive approaches.

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Multiple Choice Questions on this study

In Griffin 2025 et al., on SLN mapping with ICG, what was the histologic diagnosis of the pulmonary mass?

A. Grade 2 adenocarcinoma
B. Grade 1 adenocarcinoma
C. Carcinosarcoma
D. Primary lymphoma
E. Pulmonary histiocytosis

Answer: Grade 1 adenocarcinoma

Explanation: Histopathology confirmed a completely excised grade 1 pulmonary adenocarcinoma.
In Griffin 2025 et al., on SLN mapping with ICG, which lymph node was identified as sentinel?

A. Cranial mediastinal
B. Right tracheobronchial
C. Left tracheobronchial
D. Central mediastinal
E. Sternal

Answer: Right tracheobronchial

Explanation: NIR imaging localized the right tracheobronchial lymph node as sentinel after ICG injection.
In Griffin 2025 et al., on SLN mapping with ICG, what imaging modality was used to visualize lymphatic drainage?

A. CT-lymphography
B. Ultrasound
C. Near-infrared (NIR) imaging
D. MRI
E. Lymphoscintigraphy

Answer: Near-infrared (NIR) imaging

Explanation: NIR overlay was used intraoperatively to track lymphatic flow and identify the SLN.
In Griffin 2025 et al., on SLN mapping with ICG, how was indocyanine green administered?

A. IV bolus
B. Subcutaneous injection
C. Bronchoscopic instillation
D. Peritumoral injection under thoracoscopic guidance
E. Intranasal drip

Answer: Peritumoral injection under thoracoscopic guidance

Explanation: ICG was injected with a 22G needle into tissue adjacent to the mass thoracoscopically.
In Griffin 2025 et al., on SLN mapping with ICG, which statement best describes the clinical utility of this technique?

A. Applicable only to open surgery
B. Not feasible in dogs
C. Effective in identifying SLNs for staging
D. Poor visualization of lymphatics
E. Only useful for abdominal tumors

Answer: Effective in identifying SLNs for staging

Explanation: The method enabled safe, image-guided SLN extirpation during pulmonary surgery.

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