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Miller et al: Cooled feline intestine and fresh intestine did not differ in enterotomy leak pressure testing or in gross wall thickness measurement
Veterinary Surgery 5, 2024

🔍 Key Findings

  • No difference in initial leak pressure (ILP) or maximum intraluminal pressure (MIP) between cooled (17–29 h) and fresh enterotomy constructs.
  • Wall thickness of duodenum and jejunum did not differ between fresh and cooled samples.
  • Leak locations (suture holes vs clamp sites) were similar between groups; not statistically different.
  • Volume of infusion did not influence ILP or MIP outcomes.
  • Mean ILP values: Control = 600 mmHg (maxed), Fresh = 200 mmHg, Cooled = 131 mmHg; CE vs FE difference was not significant.
  • Intraluminal diameter was largest in the ileum, followed by jejunum and duodenum.
  • Cadaveric intestine cooled ≤29h may be reliably used in ex vivo feline leak pressure studies.
  • First report of gross small intestinal lengths by region in cats—useful for resection planning.

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← Articles

Miller et al: Cooled feline intestine and fresh intestine did not differ in enterotomy leak pressure testing or in gross wall thickness measurement
Veterinary Surgery 5, 2024

🔍 Key Findings

  • No difference in initial leak pressure (ILP) or maximum intraluminal pressure (MIP) between cooled (17–29 h) and fresh enterotomy constructs.
  • Wall thickness of duodenum and jejunum did not differ between fresh and cooled samples.
  • Leak locations (suture holes vs clamp sites) were similar between groups; not statistically different.
  • Volume of infusion did not influence ILP or MIP outcomes.
  • Mean ILP values: Control = 600 mmHg (maxed), Fresh = 200 mmHg, Cooled = 131 mmHg; CE vs FE difference was not significant.
  • Intraluminal diameter was largest in the ileum, followed by jejunum and duodenum.
  • Cadaveric intestine cooled ≤29h may be reliably used in ex vivo feline leak pressure studies.
  • First report of gross small intestinal lengths by region in cats—useful for resection planning.

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Multiple Choice Questions on this study

In Miller 2024 et al., on leak testing in cooled feline intestine, what was the finding regarding initial leak pressure (ILP) between fresh and cooled enterotomy constructs?

A. Initial leak pressure was higher in cooled constructs
B. Initial leak pressure was lower in cooled constructs
C. Initial leak pressure did not differ significantly between groups
D. Cooled constructs consistently failed at clamp sites
E. Only cooled constructs had catastrophic failures

Answer: Initial leak pressure did not differ significantly between groups

Explanation: Both ILP and MIP did not differ between cooled and fresh enterotomy groups.
In Miller 2024 et al., on leak testing in cooled feline intestine, where did most leaks initiate in both groups?

A. Suture hole
B. Clamp site
C. Serosal tear
D. Anastomotic gap
E. Mesenteric border

Answer: Suture hole

Explanation: Suture hole was the most common site of initial leakage in both groups.
In Miller 2024 et al., on leak testing in cooled feline intestine, what explanation was given for higher leak pressures compared to canine data?

A. Thicker intestinal wall in cats
B. Feline intestine naturally resists autolysis
C. Lower infusion rate allowed higher pressure before leak
D. Feline segments were pre-dilated with saline
E. Cooled tissues are inherently stronger

Answer: Lower infusion rate allowed higher pressure before leak

Explanation: Infusion at 100 mL/h allowed slower distension and higher pressures than previous canine studies.
In Miller 2024 et al., on leak testing in cooled feline intestine, what was the maximum duration of cooling tested?

A. 12 hours
B. 17 hours
C. 24 hours
D. 29 hours
E. 36 hours

Answer: 29 hours

Explanation: Cooled intestine was stored for up to 29 hours before testing.
In Miller 2024 et al., on leak testing in cooled feline intestine, what was a key implication of the intraluminal diameter findings?

A. Duodenum was significantly wider than ileum
B. Jejunum was unusable due to collapse
C. Ileum had the largest diameter, helpful for device planning
D. All regions had identical luminal diameters
E. The results showed only collapsed segments

Answer: Ileum had the largest diameter, helpful for device planning

Explanation: Ileum was widest and data may assist in future stapler selection.

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