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Renaud et al: Clinical findings and prognostic factors for immediate survival in 33 dogs undergoing surgery for biliary peritonitis
Veterinary Surgery 2, 2025

🔍 Key Findings

Mortality rate: 36% (12/33)
Cholecystectomy performed: 94% of dogs (31/33)
New significant prognostic factors for survival:

  • Hyperbilirubinemia (p = .049) — threshold = 60.5 μmol/L
  • Use of vasopressors (p = .002)
  • Renal dysfunction postoperatively (p = .008)
  • Number of postoperative complications (p = .005)

Multivariate model: Total bilirubin and number of complications best predicted survival
Septic vs nonseptic effusion: No significant difference in survival
Diagnostic imaging: Ultrasound sensitivity for extrahepatic biliary rupture = 38%
Most cultured pathogen: E. coli (80% of septic cases)

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← Articles

Renaud et al: Clinical findings and prognostic factors for immediate survival in 33 dogs undergoing surgery for biliary peritonitis
Veterinary Surgery 2, 2025

🔍 Key Findings

Mortality rate: 36% (12/33)
Cholecystectomy performed: 94% of dogs (31/33)
New significant prognostic factors for survival:

  • Hyperbilirubinemia (p = .049) — threshold = 60.5 μmol/L
  • Use of vasopressors (p = .002)
  • Renal dysfunction postoperatively (p = .008)
  • Number of postoperative complications (p = .005)

Multivariate model: Total bilirubin and number of complications best predicted survival
Septic vs nonseptic effusion: No significant difference in survival
Diagnostic imaging: Ultrasound sensitivity for extrahepatic biliary rupture = 38%
Most cultured pathogen: E. coli (80% of septic cases)

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Multiple Choice Questions on this study

In Renaud 2025 et al., on biliary peritonitis surgery, which factor was significantly associated with decreased immediate survival (p = .002)?

A. Hypoglycemia
B. Age > 10 years
C. Vasopressor use
D. Body weight < 10 kg
E. Preoperative ultrasound findings

Answer: Vasopressor use

Explanation: Use of vasopressors was associated with significantly lower immediate survival (hazard ratio 0.29, p = .002).
In Renaud 2025 et al., on biliary peritonitis surgery, which bacterial species was most frequently isolated from septic effusions?

A. Enterococcus faecalis
B. Clostridium perfringens
C. Pseudomonas aeruginosa
D. Escherichia coli
E. Staphylococcus pseudintermedius

Answer: Escherichia coli

Explanation: E. coli was cultured from 80% of septic effusions, making it the most common isolate in this cohort.
In Renaud 2025 et al., on biliary peritonitis surgery, which diagnostic tool had only 38% sensitivity for detecting biliary tract rupture?

A. Abdominal radiographs
B. Exploratory celiotomy
C. Serum bile acids
D. Ultrasound
E. CT scan

Answer: Ultrasound

Explanation: Ultrasound identified biliary rupture in only 38% of confirmed cases, highlighting its limited sensitivity.
In Renaud 2025 et al., on biliary peritonitis surgery, what procedure was performed in 94% of dogs?

A. Biliary diversion via stenting
B. Choledochotomy
C. Cholecystectomy
D. T-tube placement
E. Hepatic lobectomy

Answer: Cholecystectomy

Explanation: Cholecystectomy was performed in 94% of dogs, making it the most common surgical intervention.
In Renaud 2025 et al., on biliary peritonitis surgery, what total bilirubin threshold was associated with a 50% mortality rate?

A. 24.0 µmol/L
B. 38.5 µmol/L
C. 60.5 µmol/L
D. 76.0 µmol/L
E. 89.5 µmol/L

Answer: 60.5 µmol/L

Explanation: Total bilirubin > 60.5 µmol/L was associated with 50% mortality among dogs with biliary peritonitis.

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