Parlier et al: Prospective, randomized, clinical trial on the effects of laparoscopic insufflation pressures on portal pressures in dogs
Veterinary Surgery 4, 2024

🔍 Key Findings

Portal pressure increased proportionally with insufflation pressure: 38% at 6 mmHg, 95% at 10 mmHg, and 175% at 14 mmHg.
Exponential model: average increase of 7.45% per mmHg of insufflation pressure (CI: 4.7–10.2%).
No systemic hemodynamic adverse effects were observed; MAP remained >60 mmHg throughout.
Portal hypertension threshold (15 mmHg) predicted at ~6.4 mmHg insufflation pressure.
No statistical impact from patient weight, pressure-to-weight ratio, or order of insufflation rounds.
Measurement technique was feasible and safe, with only minor challenges (e.g., catheter kinking).
The study supports use of the lowest insufflation pressure needed for visualization to avoid portal hypertension.
Baseline portal pressures returned after desufflation, supporting comparison pre- and post-attenuation.

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Parlier et al: Prospective, randomized, clinical trial on the effects of laparoscopic insufflation pressures on portal pressures in dogs
Veterinary Surgery 4, 2024

🔍 Key Findings

Portal pressure increased proportionally with insufflation pressure: 38% at 6 mmHg, 95% at 10 mmHg, and 175% at 14 mmHg.
Exponential model: average increase of 7.45% per mmHg of insufflation pressure (CI: 4.7–10.2%).
No systemic hemodynamic adverse effects were observed; MAP remained >60 mmHg throughout.
Portal hypertension threshold (15 mmHg) predicted at ~6.4 mmHg insufflation pressure.
No statistical impact from patient weight, pressure-to-weight ratio, or order of insufflation rounds.
Measurement technique was feasible and safe, with only minor challenges (e.g., catheter kinking).
The study supports use of the lowest insufflation pressure needed for visualization to avoid portal hypertension.
Baseline portal pressures returned after desufflation, supporting comparison pre- and post-attenuation.

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Multiple Choice Questions on this study

In Parlier 2024 et al., on insufflation effects on portal pressure in dogs, what insufflation pressure was predicted to induce portal hypertension (>15 mmHg)?

A. 4.5 mmHg

B. 5.5 mmHg

C. 6.4 mmHg

D. 8 mmHg

E. 10 mmHg

Answer: 6.4 mmHg

Explanation: Portal hypertension was predicted to occur at 6.4 mmHg based on the exponential model.

In Parlier 2024 et al., on insufflation effects on portal pressure in dogs, what clinical recommendation did the authors make regarding insufflation pressure?

A. Use 14 mmHg routinely

B. Use pressure based on body weight

C. Use lowest pressure to allow visualization

D. Use high pressure only in shunt cases

E. Always use 10 mmHg

Answer: Use lowest pressure to allow visualization

Explanation: Authors recommended using the minimum insufflation pressure necessary to visualize the abdomen.

In Parlier 2024 et al., on insufflation effects on portal pressure in dogs, what was the average portal pressure increase per mmHg insufflation pressure?

A. 3.2%

B. 5.5%

C. 6.1%

D. 7.45%

E. 9.8%

Answer: 7.45%

Explanation: The exponential model found an average portal pressure increase of 7.45% per mmHg insufflation.

In Parlier 2024 et al., on insufflation effects on portal pressure in dogs, what was the observed change in portal pressure at 14 mmHg insufflation?

A. 95% increase

B. 105% increase

C. 120% increase

D. 150% increase

E. 175% increase

Answer: 175% increase

Explanation: Portal pressure increased by 175% at 14 mmHg compared to baseline.

In Parlier 2024 et al., on insufflation effects on portal pressure in dogs, which of the following factors significantly affected portal pressure measurements?

A. Dog weight

B. Insufflation round

C. Weight/pressure ratio

D. Anesthetic protocol

E. None of the above

Answer: None of the above

Explanation: No statistical effect was found from weight, ratio, or insufflation round.

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