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Thompson et al: Effects of cyanoacrylate on leakage pressures of cooled canine cadaveric jejunal enterotomies
Veterinary Surgery 2, 2024

🔍 Key Findings

  • Highest initial leak pressure (ILP) observed in the handsewn + cyanoacrylate (HS + CE) group: 83.3 ± 4.6 mmHg (p < .001 vs. others).
  • Lowest ILP: cyanoacrylate-only group (CE): 18.6 ± 3.5 mmHg.
  • No significant MIP difference between handsewn (HSE) and HS + CE groups (p = .19); CE had significantly lower MIP (22.7 mmHg).
  • Leak location:
    • HSE: 60% from suture holes
    • CE: 100% from incisional line
    • HS + CE: 60% from incisional line, 40% from suture holes
  • Authors conclude cyanoacrylate augmentation significantly increases ILP and could reduce enterotomy leakage risk.

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← Articles

Thompson et al: Effects of cyanoacrylate on leakage pressures of cooled canine cadaveric jejunal enterotomies
Veterinary Surgery 2, 2024

🔍 Key Findings

  • Highest initial leak pressure (ILP) observed in the handsewn + cyanoacrylate (HS + CE) group: 83.3 ± 4.6 mmHg (p < .001 vs. others).
  • Lowest ILP: cyanoacrylate-only group (CE): 18.6 ± 3.5 mmHg.
  • No significant MIP difference between handsewn (HSE) and HS + CE groups (p = .19); CE had significantly lower MIP (22.7 mmHg).
  • Leak location:
    • HSE: 60% from suture holes
    • CE: 100% from incisional line
    • HS + CE: 60% from incisional line, 40% from suture holes
  • Authors conclude cyanoacrylate augmentation significantly increases ILP and could reduce enterotomy leakage risk.

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Multiple Choice Questions on this study

In Thompson 2024 et al., on cyanoacrylate enterotomy sealants, what is the suggested clinical implication of adding cyanoacrylate to a handsewn enterotomy repair?

A. Delays healing due to rigidity
B. Increases incisional leakage risk
C. Provides no added benefit
D. Reduces enterotomy leakage by enhancing sealing
E. Replaces need for sutures

Answer: Reduces enterotomy leakage by enhancing sealing

Explanation: The addition of CE significantly increased ILP and reduced leak rate, supporting its potential use adjunctively.
In Thompson 2024 et al., on cyanoacrylate enterotomy sealants, what was the most common leak location in the cyanoacrylate-only (CE) group?

A. Suture hole
B. Transverse staple line
C. Incisional line
D. Serosal edge
E. Mesenteric border

Answer: Incisional line

Explanation: 100% of leaks in the CE group originated from the incisional line.
In Thompson 2024 et al., on cyanoacrylate enterotomy sealants, which group had the lowest maximum intraluminal pressure (MIP)?

A. HSE
B. HS + CE
C. Stapled
D. Cyanoacrylate only
E. Control

Answer: Cyanoacrylate only

Explanation: The CE group had the lowest MIP (mean 22.7 mmHg), significantly lower than suture-based groups.
In Thompson 2024 et al., on cyanoacrylate enterotomy sealants, how did the maximum intraluminal pressure (MIP) compare between the handsewn (HSE) and HS + CE groups?

A. HS + CE significantly higher
B. HSE significantly higher
C. Both significantly lower than CE
D. No significant difference
E. HS + CE was lower but significant

Answer: No significant difference

Explanation: The HSE and HS + CE groups had comparable MIP values (p = .19).
In Thompson 2024 et al., on cyanoacrylate enterotomy sealants, which group had the highest initial leak pressure (ILP)?

A. Cyanoacrylate only
B. Handsewn only
C. Stapled only
D. Handsewn + cyanoacrylate
E. Unrepaired control

Answer: Handsewn + cyanoacrylate

Explanation: The HS + CE group achieved the highest ILP (83.3 mmHg), significantly exceeding all others (p < .001).

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